Kary Uni Description

Kary Uni is an orange sterile aqueous suspension. Each mL contains 0.05mg of pirenoxine. Its pH is 3.4-4.0 and its osmotic pressure ratio is 0.9-1.2.
There are various theories for the development of senile cataract, but the mechanism has not been elucidated. Ophthalmic preparations of pirenoxine (1-hydroxy-5-oxo-5H-pyrido[3,2-α]phenoxazine-3-carboxylic acid) were developed, based on the quinoid theory proposed by Ogino in 1957 and is recognized to be clinically effective for the treatment of cataract.
Kary Uni ophthalmic suspension is an aqueous ophthalmic suspension which contains pirenoxine as an active ingredient. Immediately after topical application, the pH of this preparation becomes equivalent to that of the lacrimal fluid, the suspended pirenoxine particles being dissolved rapidly in the lacrimal fluid.
Excipients/Inactive Ingredients: It also contains disodium edetate hydrate, benzalkonium chloride, concentrated glycerin, and polyoxyethylene hydrogenated castor oil 60 as additives.